This is a very comprehensive list of SW Florida venues that have offered live Blues music in the recent past. Venues do come and go, so take this list with a 'grain of salt' as they say. Some venues can present large acts, some can only handle one or two pieces.
 

Venue Name	Street	City	St	Zip
Back Street Sports Bar	915 SE 47TH Ter	Cape Coral	FL	33904-9009
Paradise Tiki Hut		Cape Coral	FL
The Dek		Cape Coral	FL
Cruisers Lounge		Cape Coral	FL
Leapin Lizard	1719 Cape Coral Pkwy E	Cape Coral	FL	33904
J.J. Muggs	10365 Royal Palm Blvd.	Coral Springs	FL
Anthony's On The Beach		Fort Myers	FL
San Carlos Country Club		Fort Myers	FL
The Beached Whale	1249 Estero Boulevard	Fort Myers	FL	33931
Buckingham Bar	5641 Buckingham Rd	Fort Myers	FL	33905
City Tavern	2206 Bay St	Fort Myers	FL	33901
L J's Lounge & Package	16500 State Road 31	Fort Myers	FL	33905
Casey's Alley	2555 Estero Blvd	Fort Myers Beach	FL	33931
Windjammer	16681 McGregor Blvd	Fort Myers Beach	FL
Bert's Bar & Grill	4271 Pine Island Rd.	Matlacha	FL	33993
Benedetto's Steakhouse and Martini Bar		Punta Gorda	FL
Harpoon Harry's		Punta Gorda	FL
17 Lounge	3149 Duncan Rd	Punta Gorda	FL	33982
Last Chance Saloon	25354 Marion Ave	Punta Gorda	FL	33950
Slip Knot	Tamiami Trail	Punta Gorda	FL
Brewski's	Tamiami Trail	North Port	FL
Riverside Lounge & Restaurant	14000 Tamiami Trl	North Port	FL	34287-2208
Coral Rock Café	Tamiami Trail	Port Charlotte	FL
E.J.'s Frosted Mug	4104 El Jobean Road	Port Charlotte	FL	33952
Portofino		Port Charlotte	FL
Willie's	4095 Tamiami Trl Ste A	Port Charlotte	FL	33952-9212
Banditos	5665 McCall Rd	Port Charlotte	FL	33981
Boomers Sports Bar-Night Club	2360 Tamiami Trail	Port Charlotte	FL	33952-3924
Gatorz Bar	3816 Tamiami Trail	Port Charlotte	FL	33952
Hoosier's Bar And Grille	Tamiami Trail	Osprey	FL
Bacalao's Restaurant & Bar	1100 N Tuttle Ave	Sarasota	FL	34237
BC's Recovery Room	2119 Siesta Key	Sarasota	FL
Cabana Inn	2420 Tamiami Trail	Sarasota	FL	34239
T Katz Pub	2920 Beneva Road	Sarasota	FL	34232
The Old Packinghouse	987 S. Packinghouse Rd.	Sarasota	FL	34232
Kirby's	2460 Stickney Pt. Rd.	Sarasota	FL	34232
Five O'Clock Club	1930 Hillview St.	Sarasota	FL	34239
Pastimes Pub	6540 Superior Ave.	Sarasota	FL	34231
Will's Honky Tonk	5748 Swift Rd	Sarasota	FL	34232
Gilligan's	Siesta Key Village	Siesta Key	FL	34232
Siesta Key Oyster Bar	5238 Ocean Boulevard	Siesta Key	FL	34232
Speakeasy	5254 Ocean Blvd	Siesta Key	FL	34232
Venice Sharks Tooth Festival	Venice Airport Festival Grounds	Venice	FL	34292
Frisky Mermaid Bar & Grille		Amelia Island	FL
The Frisky Mermaid	22 South 3rd Street Fernandina Beach	Amelia Island	FL	32034
Sidelines Sports Bar	250 Apollo Beach Blvd.	Apollo Beach	FL
Garrett's Place	5813 US Hwy 41 No	Apollo Beach	FL	33572
Accolades Bar	3052 Old Dixie Highway	Auburndale	FL
Beacon Woods Civic Association	12440 Clocktower Dr.	Bayonnet Point	FL
Back Room Blues Bar		Boca Raton	FL
Sneaky Pete's		Bonita Springs	FL
Barnacles Restaurant	926 Providence Road	Brandon	FL	33511
Fox & Hounds	229 E. Brandon Blvd. Hwy. 60	Brandon	FL
O'Brien's Irish Pub	Corner Lumsden & King Aves.	Brandon	FL
Pirate's Cove Bar & Grill	827 West Bloomingdale Ave	Brandon	FL	33511
Shakers Grill & Club	31077 Cortez SR 50	Brooksville	FL	34602
Hernando Park	205 East Fort Dade Ave.	Brooksville	FL
Cafe Del Mar	211 S. Atlantic Blvd.	Broward County	FL	33020
Dubliner Irish Pub North		Citrus Park	FL
Frenchy's Rockaway Grill	7 Rockaway St.	Clearwater	FL	33767
Gecko's	2914 Roosevelt Blvd.	Clearwater	FL	33760
Pastino's	1750 Clearwater Largo Rd.	Clearwater	FL	33756
Quaker Steak and Lube	10400 49th St.	Clearwater	FL
Clearwater Sea Blues Festival	Coachman Park	Clearwater	FL
Coachman Park		Clearwater	FL
Octagon Arts Center		Clearwater	FL
Ruth Eckerd Hall	1111 McMullen Booth Road	Clearwater	FL	33759
The Junction	705 Franklin St.	Clearwater	FL	33756
Big Daddy Dave's Jazz & Blues Club		Cocoa	FL
Heidi's Jazz Club		Cocoa Beach	FL
The Beach Shack	1 Minutemen Causeway	Cocoa Beach	FL
Titanic Brewery & Restaurant	5813 Ponce de Leon Blvd.	Coral Gables	FL	33146
Fritz & Franz Bierhaus	60 Merrick Way	Coral Gables	FL	33134
Osceola Tavern	13941 7th St. Hwy 301	Dade City	FL	33525
Bank & Blues Club	9 S. Wild Olive Ave.	Daytona Beach	FL	32118
caffe da vinci		DeLand	FL
City Limits	29 SE Second Ave.	Delray	FL	33444
Funky Blues Shack		Destin	FL
Cricketers	2634 Bayshore Boulevard	Dunedin	FL	34698
Dunedin Brewery		Dunedin	FL	34698
Fat Daddy's	1780 Main St.	Dunedin	FL
Got Wine & Cigars	662 Main St.	Dunedin	FL
Joli-mon's	941 Huntley Ave.	Dunedin	FL
T.J.'s Main Street	1433 Main St.	Dunedin	FL	34698
The Hideaway	2182 Main Street	Dunedin	FL	34698
Back Room Bluz	24 E. Magnolia Ste. #5	Eustis	FL	32726
Sleepy Hollow	Rt. 41	Floral City	FL
Cheers		Fort Lauderdale	FL
Blue Martini	2432 East Sunrise Blvd #1008	Fort Lauderdale	FL	33304
Downtowner Saloon	408 South Andrews Ave.	Fort Lauderdale	FL	33301
Jesters Bar and Grill	801 W. Cypress Creek Rd.	Fort Lauderdale	FL	33309
Last Call	5280 N. State Road 7	Fort Lauderdale	FL
O'Hara's Jazz & Blues Cafe' 722 E.	Las Olas Blvd.	Fort Lauderdale	FL	33301
Original Fat Cats		Fort Lauderdale	FL
Governor's Grill	122 North 2nd St.	Fort Pierce	FL
Clubhouse Grille		Gainesville	FL
Down Town Plaza		Gainesville	FL
Calico Jack's		Gainesville	FL
Club Red		Gainesville	FL
Common Grounds		Gainesville	FL
Decadence		Gainesville	FL
Eddie C's		Gainesville	FL
Gulfport Casino	5500 Shore Blvd So	Gulfport	FL
Gulfport on the Rocks	5413 Shore Blvd.	Gulfport	FL
Connie's Clubhouse Grill		Hollywood	FL
O'Hara's Hollywood	1903 Hollywood Blvd.	Hollywood	FL	3302
Sushi Blues Cafe'	2009 Harrison St.	Hollywood	FL	33020
The Universe Cafe	1925 Hollywood Blvd.	Hollywood	FL	33020
Club M	2037 Hollywood Blvd	Hollywood	FL	33020
JAZZIZ Bistro & Live Music		Hollywood	FL
Kelly's Pub	1832 Harrison St.	Hollywood	FL	33020
Main Street Cafe		Homestead	FL
MacRae's Dockside	County Road 490	Homossasa	FL
Macrae's Tiki Hut		Homossasa	FL
Cheap Charlies	11909 State Road 52	Hudson	FL	34669
Cricketers	7306 SR 52	Hudson	FL	34667
Governor's Lounge	SR 52	Hudson	FL
Lou's Blues	3191 No. A1A	Indialantic	FL
Mojo's Kitchen	1500 Beach Blvd.	Jacksonville Beach	FL	32250
Blue Note Cafe'	201 US Highway 1	Jupiter	FL	33477
Schooner Warf		Key West	FL
Green Parrot Bar	601 Whitehead St.	Key West	FL	33040
House of Blues	1490 E. Buena Vista Dr.	Lake Buena Vista	FL	32830
The Orange Door	798 10th St.	Lake Park	FL	33403
R & L Pub	126 1st St. N.	Lake Wales	FL
Bamboo Room	25 South J St.	Lake Worth	FL	33460
Shuckey's Oyster Bar	1401 E. Gary Road	Lakeland	FL
Arts On The Park Gallery	115 N. Kentucky Ave	Lakeland	FL
Music Ranch		Lakeland	FL
Ybor Cigar & Spirits	5263 S. Florida Ave.	Lakeland	FL
Rapscallions	4422 land O' Lakes Blvd	Land O' Lakes	FL
Largo Sports Bar & Grille	776 Missouri Ave.	Largo	FL
Aging Still	11561 Walsingham Rd.	Largo	FL
Rockwell's Corner Pub	10801 Starkey Rd.	Largo	FL
Sundown Saloon	12553 Ulmerton Road	Largo	FL	33774
The Sports Bar & Grill	776 Missouri Avenue	Largo	FL
Rosey Baby		Lauderhill	FL
City Of Leesburg	New Year's Eve Downtown Street Party	Leesburg	FL
Leesburg BikeFest		Leesburg	FL
Copper Rocket Pub		Maitland	FL
Marco Island's Simply Silly Celebration	Mackle Park	Marco Island	FL
McIntosh Cafe		McIntosh	FL
Sebastian Beach Inn	7035 S. Hwy. A1A "The Beach Road"	Melbourne Beach	FL	32951
Falcon's Roost		Merritt Island	FL
Bullfrog Eatz		Miami	FL
Little Hoolies	13135 SW 89th Pl.	Miami	FL	33176-5813
Tobacco Road	626 S. Miami Ave.	Miami	FL	33130
Jazid		Miami Beach	FL
The Wine Cellar		N. Redington Beach	FL
Saltwater Cowboys Raw Bar		Naples	FL
Chasco Fiesta	Sims Park	New Port Richey	FL
Cotee River Seafood Festival	Simms Park	New Port Richey	FL
Bourbon Street Nightclub	4331 US Hwy 19	New Port Richey	FL	34652
Luna Star Cafe	775 NE 125 St.	North Miami	FL
Alligator Alley	1321 East Commercial Blvd.	Oakland Park	FL	33334
Oldsmar Blues Fest - R.E. Olds Park	107 Shore Dr. W.	Oldsmar	FL
Cyprus Club and Ballroom		Orange Park	FL
B. B. King's Club		Orlando	FL	32816
House of Blues	Downtown Disney	Orlando	FL	32830
Tanquerays Bar & Grill	100 S. Orange Ave.	Orlando	FL	32801
Ozona Blue	655 Orange St.	Palm Harbor	FL	34683
Schooners		Panama City Beach	FL
Cajun Café On The Bayou		Pinellas Park	FL
Quaker Steak and Lube	10400 49th Street N.	Pinellas Park	FL
Beale Street Bar and Grill		Pompano	FL
Chit Chat's Lounge	826 N. Federal Hwy.	Pompano Beach	FL	33062
Grille's		Port Canaveral	FL
Charlie's Hideaway	11720 USHighway 19	Port Richey	FL	34668
Whistle Stop Grill	915 Main St.	Safety Harbor	FL	34695
Safety Harbor Gazebo		Safety Harbor	FL
The Alley	114 S. Park Ave.	Sanford	FL
Earl's Hideaway Lounge		Sebastian	FL
Lenny's	718 E. MLK	Seffner	FL	33584
Billy Bob's Beach Bar	1001 Hwy 92 West	Seffner	FL	33584
Boomerz		Seminole	FL
Blue Note Lounge	4658 Commercial Way US19	Spring Hill	FL
Pickled Parrot	5526 Commercial Way	Spring Hill	FL	34606
VFW	Springhill Dr.	Spring Hill	FL
San Sebastian Winery	157 King Street	St. Augustine	FL	32084
Biff Burger	3939 49th St N	St. Petersburg	FL	33709-5731
Bishop Tavern	260 1st Ave No	St. Petersburg	FL	33701
Cafe Alma	260 1st Ave So.	St. Petersburg	FL	33701
Fortunato's	259 Central Ave.	St. Petersburg	FL	33701
Limey's Pub	1492 4th St. N	St. Petersburg	FL	33701
Ringside Cafe	2742 Fourth St. N.	St. Petersburg	FL	33704
Sneaky D's	4808 CR 16	St. Petersburg	FL	33709
Baywalk	2nd Ave. N.	St. Petersburg	FL	33701
Heart for the Arts	2300 62nd Ave	St. Petersburg	FL
Jingle Bell Run		St. Petersburg	FL
4th St. Cigars	2900 4th St N	St. Petersburg	FL	33704
Abbey Road Pub	974 58th St. N	St. Petersburg	FL
Beer, Bikes & Babes	5304 66th St N	St. Petersburg	FL
Dave's Aqua Lounge	10820 Gandy Blvd. No.	St. Petersburg	FL	33702
Fast Eddie's	5017 66th St. N.	St. Petersburg	FL	33709
Tavern at Bayboro	121 7th Ave. S.	St. Petersburg	FL
Sloppy Pelican	677 75th Ave	St. Petersburg Beach	FL	33706-1835
Swigwam Beach Bar	Travelodge - 6300 Gulf Blvd.	St. Petersburg Beach	FL	33706
Blue Parrot	85 Corey Circle	St. Petersburg Beach	FL
Jeff's Bent Elbow	7370 Gulf Blvd.	St. Petersburg Beach	FL
Sunset Bar	15900 Gulf Blvd.	St. Petersburg Beach	FL
Buzz's Bar	8931 W. Oakland Park Blvd.	Sunrise	FL
Ka'Tiki	8801 W. Gulf Blvd.	Sunset Beach	FL
Cafe Cabernet		Tallahassee	FL
American Legion		Tallahassee	FL
Bradfordville Blues Club	7152 Moses Lane	Tallahassee	FL	32309
Dave's CC Club		Tallahassee	FL
42nd St Bistro	516 S. Howard Ave.	Tampa	FL	33606
Blue Shark	1502 E. 7th Ave. / Ybor City	Tampa	FL	33605
Bootleggers	5527 Sheldon Rd.	Tampa	FL	33615
Johnny G's Restaurant & Lounge		Tampa	FL
Skipper's Smokehouse	910 Skipper Rd.	Tampa	FL	33613
Barry Motor Sports	2316 W Hillsborough Ave	Tampa	FL	33603
St. Pete Times Forum		Tampa	FL
Tampa Bay Performing Arts Center		Tampa	FL
Tampa Theatre	711 Franklin Street	Tampa	FL	33602
The Fox,  Lincoln Center	5401 W Kennedy Blvd.	Tampa	FL
The Orpheum	1902 N Avenida Republica De Cuba	Tampa	FL
Gaspar's Grotto	1805 7th Ave E	Tampa	FL	33605
Good Time Charlie's Pub	4030 West Waters Ave	Tampa	FL	33614
Goodfellas	4802 Gunn Highway Plantation Sh. Ctr.	Tampa	FL
Green Iguana	4029 S. Westshore Blvd.	Tampa	FL	33611
DC's Downtown Bar & Grill	110 E. Tarpon Ave.	Tarpon Springs	FL	34689
Tarpon Springs Performing Art Center		Tarpon Springs	FL
Snapper's	36657 US 19 N	Tarpon Springs	FL
The Zone Art Music Lounge	121 E. Tarpon Ave.	Tarpon Springs	FL	34689
J J Mugz	1948 State Rd. 60	Valrico	FL	33594
Po' Boys Creole Cafe	3345 Lithia Pinecrest Rd.